malignant transformation
noun
                                
              
          
                                                      : the transformation that a cell undergoes to become a rapidly dividing tumor-producing cell                                      
                
                                
            also                
          
                                                      : the transformation of a mass of cells or a tissue into a rapidly growing tumor                                       
              
                             
            malignant transformation of certain warts    
                         
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  Merriam-Webster unabridged




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